Objective To explore the effect of swallowing training based on virtual reality technology on recovery of patients with post-stroke dysphagia. Methods A total of 94 stroke patients with dysphagia were chronologically divided into a traditional group (n=47, receiving routine swallowing training) or a study group (n=47, receiving virtual reality-based swallowing training).The intervention lasted 4 weeks.The swallowing function, grading of aspiration risk, incidence of aspiration, and quality of life were compared between the two groups. Results Totally, 44 in the traditional group and 45 in the study group completed the study.Significant main effect of group, main effect of time, and group-by-time interaction effect were found in the swallowing function scores (all P＜0.05).After the intervention, the study group had milder aspiration risk grading, lower incidence of aspiration, and lower score for the Dysphagia Handicap Index compared to the traditional group (all P＜0.05). Conclusion The virtual reality game for swallowing training which integrates immersive scene, functional task and interactive feedback can effectively improve the swallowing function of patients with dysphagia after stroke, reduce the incidence of aspiration and improve swallowing-related quality of life.