Objective To investigate the current status of flourishing among nurses working in the emergency department, to analyze its influencing factors, and to provide a reference for formulating and conducting targeted nursing intervention. Methods A convenience sampling method was used to select 365 nurses working in the emergency department from 5 tertiary grade A general hospitals in Changchun city. A questionnaire survey was conducted using a general information questionnaire, The Flourishing Scale, the Nurses′ Perceived Professional Benefits Scale, the Perceived Social Support Scale, and the Occupational Coping Self-Efficacy Scale For Nurses. Results The nurses scored （32.21±3.06） points in flourishing. Multiple linear regression analysis showed that personality type, job ranking, monthly income, whether holding an administrative position, perceived professional benefits, perceived social support, and occupational coping self-efficacy were influencing factors of flourishing among nurses working in the emergency department （P＜0.05）. Conclusion The level of flourishing among emergency department nurses was found to be moderate. Nursing managers should implement targeted interventions based on the identified influencing factors, with a particular focus on nurses who are introverted, have a lower job ranking, have a lower income, or hold no administrative position. Enhancing their perceived professional benefits, perceived social support, and occupational coping self-efficacy can promote their flourishing, thereby fostering the stability and development of the emergency nursing workforce.