In 2025, the Therapeutic Wound and Skin Cleansing: Clinical Evidence and Recommendations, released by the International Wound Infection Institute, systematically addresses on the definition and scope of therapeutic wound cleansing, key elements in its implementation, and approaches to managing pain during the procedure. Based on these aspects, the consensus presents 13 integrated recommendations. This article provides an interpretation of the consensus, aiming to enhance healthcare professionals′ understanding of the latest therapeutic cleansing guidelines and to promote their standardized application in clinical nursing practice.