Objective To understand the emergency response ability of nurse assistants in nursing homes, and to analyze its influencing factors, so as to provide references for optimizing the training program of emergency skills of nurse assistants. Methods A total of 356 nurse assistants from 6 nursing homes in Tangshan were conveniently selected, then they were investigated by using a ge-neral information questionnaire, the Emergency Response Ability Questionnaire of the Nurse Assistants in Nursing Homes, and the Care Neglect Scale of the Nurse Assistants.The influencing factors of emergency response ability were analyzed by univariate analysis, correlation analysis and multiple linear regression analysis. Results The participants′ score of emergency response ability was (171.47±15.69) points.The results of multiple linear regression analysis showed that, marital status, working years, monthly income, successful emergency response experience, degree of institutional cooperation, whether colleagues would share emergency skills, and care neglect were the influencing factors of emergency response ability of nurse assistants in nursing homes (all P＜0.05). Conclusion The emergency response ability of nurse assistants in nursing homes is at a medium and above level.Nursing homes should constantly improve the salary incentive system, create a team atmosphere of mutual assistance, strengthen quality management, and regularly carry out emergency training and exercises to improve the emergency response ability of nurse assistants.