肾病综合征患儿营养管理的最佳证据总结
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女,硕士,主管护师,护理部干事

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广东省护士协会资助项目(gdshsxh2023qn08)


Best evidence synthesis for nutritional management in children with nephrotic syndrome
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    目的 系统整合肾病综合征患儿营养管理的最佳证据,为临床制订基于证据的肾病综合征患者营养管理模式提供循证决策依据。方法 计算机系统检索临床决策支持系统、指南网及肾病综合征专业相关学术组织等国内外数据库,检索文献类型包括指南、专家共识、临床决策、推荐实践、系统评价、随机对照试验等,检索时限为建库至2025年9月。 由2名受过系统循证实践课程培训的研究者独立进行评价文献质量和证据汇总。结果 共纳入13篇文献(临床决策1篇、指南9篇、专家共识3篇),从营养评估与多学科协作、能量管理、蛋白质管理、盐与液体管理、维生素D与钙、微量元素、特殊饮食7个维度总结24条证据。结论 本研究汇总的肾病综合征患儿营养管理相关证据具有科学性,医护人员在临床应用相关证据条目时应根据患儿个体情况,审慎制订营养干预方案,以促进患者利益最大化。

    Abstract:

    Objective To systematically integrate the best available evidence on nutritional management for children with nephrotic syndrome, thereby providing an evidence-based foundation for developing clinical nutrition management protocols. Methods We comprehensively searched electronic databases (including clinical decision support systems, guideline repositories, and professional organizations related to nephrotic syndrome) for literature published from database inception to September 2025. Eligible publications included clinical guidelines, expert consensus reports, clinical decisions, practice recommendations, systematic reviews, and RCTs. Two researchers trained in evidence-based practice independently evaluated study quality and extracted the evidence. Results Thirteen publications were included (1 clinical decision, 9 guidelines, 3 expert consensus reports). Twenty-four evidence-based recommendations were synthesized across seven domains:nutritional assessment and multidisciplinary collaboration;energy management;protein management;sodium and fluid management;vitamin D and calcium supplementation;trace element regulation;therapeutic diets. Conclusion This evidence summary provides scientifically validated guidance for nutritional management in pediatric nephrotic syndrome. Healthcare professionals should judiciously adapt these recommendations to individual patient contexts when implementing nutritional interventions to maximize clinical benefits.

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陈连华,陈素华,林丹妮,刘绵珠,陈梦云,林淡珠,黄琼珊,许金微.肾病综合征患儿营养管理的最佳证据总结[J].护理学杂志,2026,41(10):111-115

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  • 收稿日期:2025-12-08
  • 最后修改日期:2026-02-26
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  • 在线发布日期: 2026-06-15