This review synthesizes current evidence on cancer information avoidance, focusing on its conceptualization, assessment instruments, prevalence among patients with and without cancer, associated influencing factors (including information factors, sociodemographic factors, fatalism, cancer fear and worry, health literacy, self-efficacy), and existing intervention approaches, including emotion-regulation strategies as well as patient-centered communication. In addition, implications for nursing practice are discussed. The aim of this review is to provide a theoretical and practical reference for future research and clinical initiatives targeting cancer information avoidance.