This article summarizes the nursing experience of a patient with post-stroke motor dysfunction in the plateau phase of rehabilitation who received non-invasive brain-computer interface (BCI) therapy under a doctor-engineer-nurse integration model. Key nursing considerations included the establishment of a doctor-engineer-nurse collaborative pathway integrating conventional rehabilitation with non-invasive BCI therapy; implementation of adaptive nursing based on multi-stage assessment and collaborative decision-making; synchronous nursing involving treatment response monitoring and dynamic intervention; and comprehensive nursing integrating behavioral guidance with structured empowerment.After eight weeks of intervention, the patient′s near-infrared whole-brain functional connectivity strength increased from 0.45 to 0.78, and the number of functional connections increased from 94.0 to 224.0.The Fugl-Meyer Assessment Scale score improved from 60 to 86; the modified Ashworth spasticity grade of the affected hand decreased from 1+ to 0; the modified Barthel Index score increased from 80 to 95; the anxiety score of the Hospital Anxiety and Depression Scale decreased from 10 to 5, and the depression score from 8 to 3; and the Stroke Self-Efficacy Questionnaire score increased from 68 to 94.At the 3-month follow-up after discharge, the patients had returned to regular daily activities.